What is a Diphoterine® Solution?
Diphoterine® Solution is a unique solution for the Emergency First Aid decontamination of chemical splashes in the eyes or on the skin.
*IMPORTANT (It has limited efficacy on Hydrofluoric Acid – please use Hexafluorine® Solution)
- Diphoterine® Solution is an aqueous, polyvalent, washing solution that is highly effective against all kinds of corrosive and irritant chemicals.
- Diphoterine® Solution is an amphoteric, chelating molecule with at least one site able to rapidly and effectively absorb and neutralise the aggressive chemical molecule to prevent the 6 possible reactions (acids, bases, oxidizers, reducing agents, solvents, chelating agents)
- Diphoterine® Solution is hypertonic which, when applied to the eye or the skin, creates an osmotic pressure that attracts the aggressive chemical that may have already penetrated into the tissue, neutralises its aggressive action and carries it safely away.
Diphotérine® Solution attracts the
chemical product in contact with the tissue
The acid site of Diphotérine® Solution
fixes and then inactivates the bases
The basic site of Diphotérine® Solution fixes and then inactivates the acid.It is by the combination of these properties that Diphoterine® Solution is uniquely able to achieve the three elements demanded for effective Emergency First Aid of a chemical splash:
- Removal of chemical from the surface of the tissue.
- Absorptionn and neutralisation of the aggressive chemical molecule remaining on the tissue surface.
- Attraction, absorption and neutralisation of the aggressive chemical molecule already penetrating the tissue.
Recent comparative studies have shown the possibility of improving on washing with water – see Figure 1.
Figure 1
| WATER | Diphoterine® Solution | ||
| Advantages | Limitations | Advantages | Limitations |
| Chemical agent at the surface of the affected tissues carried away by the mechanical washing action | Chemical agent at the surface of the affected tissues carried away by the mechanical washing action | ||
| Dilution | Dilution | ||
| Polyvalent | Polyvalent | Polyvalent: | |
| Theoretical effectiveness proven on major chemical groups | |||
| Should be verified case by case for specific chemical agents | |||
| Hypotonic: | Hypertonic: | ||
| Favours a part of the chemical agent’s penetration into the tissue, especially in eyes | Stops the chemical agent’s penetration of the tissue and carries the chemical away from the interior to the exterior of the tissue | ||
| No action on corrosives or irritants | “Neutralizing” action on the potentially irritating or corrosive nature of the chemical agent | ||
| Development of the chemical burn | Stops the development of the burn | ||
| Amphoteric: | |||
| Allows a rapid return to a physiological pH | |||
| Intervention time: the first 10 seconds | Intervention time: the first minute | ||
| Possibility of serious physical after-effects, which may even be fatal | Decrease or absence of after-effects | ||
| Prevents chemical burns | |||
| In certain cases, complex secondary treatment with reconstructive surgery | Decrease or absence of secondary treatment prevents chemical burns | A medical consultation is necessary in every case | |
| Decrease in work loss | |||
| Non toxic | Non toxic, sterile | Expiration date must be observed | |
Diphoterine® Solution is a Sterile - Medical Device, Class IIa and conforms to EN15154 – Parts 3 and 4. It is safe to use on both skin and eyes.
Non Irritating to:
- (the eyes) - Graefe’s Arch Exp Opthalmol202.240.308-313/Safepharm Laboratories Limited UK 133/4
- (the skin) - Integra, Italy 2005-024
Non Cytotoxic - Integra, Italy REL/003/06/IRRC/ELB, ISO 10993-5 standard
Non Sensitizing - CERB, France 20030418ST
Non Toxic by:
- (Ingestion) - International Centre of Toxicology, France 6564 TAR
- (Skin) - Safepharm laboratories Limited UK 133/9
- (Iv injection) - CERB, France 20030856ST
